Our shared services team manages procure to pay activities for Ionis Pharmaceuticals,
Inc. and Akcea Therapeutics, Inc. We take pride in the strong, collaborative
relationships we have built with our suppliers. It is important that our interactions are
productive and efficient. We are continuously looking for solutions that provide us with
better ways to communicate with you.

We use a portal, called the Coupa Supplier Portal (CSP), to manage transactions with
our suppliers. The portal improves the accuracy and speed of the payment process and
gives our suppliers instant access to payment information. Suppliers can use the Portal
to:

• Maintain supplier information
• View purchase orders
• Create and send invoices
• View payment status

The Coupa Portal provides several benefits for our suppliers:

Signing up for the Portal

If you are a new supplier, you should have already received an email invite to register
for the Portal. To request access to the Portal click here.

The Portal is the most efficient way to get your invoice paid. However, you can also
submit your invoices by two other electronic methods:

• Actionable Email: You can act directly from your email inbox and create invoices
  directly from the purchase order.
• cXML Transmission: You can send invoice information in a cXML format, and
  post the file directly to our procurement system.

Invoice Submission Requirements

• Invoices must be attached to your submission as a single pdf readable document
• The invoice must include a valid purchase order number; without a valid purchase
  order number the invoice will not be paid; it will be incumbent upon the supplier to
  obtain a valid purchase order number
• An invoice should reference one purchase order only
• Each invoice line must also include a reference to the corresponding purchase order
  line number for purchase orders with multiple lines; suppliers using the Coupa
  Supplier Portal will be able to view their purchase orders to ensure billings are
  constructed accurately
• The invoice currency must be clearly indicated on the invoice

Supplier Payment Options

Suppliers may select from several payment methods:

• Check or Wire – By default, all US suppliers are paid by check and all non-US
  suppliers are paid by wire.
• ACH – US suppliers may select to be paid via ACH. This payment method
  requires the supplier to sign up for the Coupa Supplier Portal in order to retrieve
  remittance information for payments.
• Procure to Pay Card – Suppliers may request to be paid via the Procure to Pay
  credit card program. Under this payment method, suppliers may be eligible for
  more favorable payment terms.

Payments for invoices not submitted through the portal or one of the other two
electronic methods noted above may not be made timely as they are outside of our
automated process.

For questions about payment method options and invoice delivery options,
suppliers click here.

Click here for current PO Terms and Conditions (effective 3/7/2019)

Click here for prior PO Terms and Conditions (effective prior to 3/7/2019)