Click on the tabs below to learn more about each of the different grant programs with IONIS, qualifications and requirements for each, and deadlines for submissions.
Investigator Initiated Research (IIR) Program
Ionis Young Investigator Grant Program
Independent Medical Education Program
Investigator Initiated Research (IIR) Program
As a part of our commitment to discover, develop, and deliver medicines to the patients who depend on us, we believe in supporting investigator-initiated research (IIR) to advance medical and scientific knowledge in our research areas of interest.
We define IIR as unsolicited research conceived, initiated, and conducted independently of Ionis. An external investigator serves as the sponsor, and with their institution, is wholly responsible for the design, implementation, conduct of the research, data collection, data interpretation, publication, and all compliance, quality, and regulatory requirements.
IIR proposals are evaluated on scientific merit, alignment with our research areas of interest, and availability of resources. Submission of a proposal does not guarantee Ionis' support.
Research Areas of Interest
Specific aspects of Severe Hypertriglyceridemia (sHTG) and Familial Chylomicronemia Syndrome (FCS) Disease, including:
Diagnosis and recognition of disease
Burden of disease
Exploring the effects of sHTG and ApoC-III on the Cardiovascular and Endocrine Systems
Mode of action, potential pleiotropic effects, and biochemical pathways of ApoC-III regulation
How to submit an IIR grant application
Please submit grant proposal applications through our online Ionis Research Grants portal by clicking here: Apply Now. If a proposal is of interest, a request for full protocol submission will be issued.
If you have any questions regarding the Ionis IIR Grant program, please email [email protected]
For Technical Support with the Ionis IIR Portal, please contact SteepRock Client Services via email at [email protected] or phone at +1 (718) 576-1406 (M-F 8am – 6pm US ET).
Ionis Young Investigator Grant Program
What is the Ionis Young Investigator Grant?
Ionis Pharmaceuticals is pleased to announce the Ionis Young Investigator Grant (YIG). This grant was recently created by the division of CardioRenal-Metabolism within Medical Affairs to recognize early career investigators who are performing high quality research in the field of severe hypertriglyceridemia. Ionis values developing clinicians and scientists who will influence the field and support new research for years to come.
Who is Eligible?
The Ionis YIG is a grant aimed at providing research grants to fellows who are at eligible academic or non-profit institutions and submit innovative research proposals in the areas of translational, clinical, or applied research. The Ionis YIG encourages early stage scientific investigators of promise to apply, who are engaged in cutting-edge research on the topic of severe hypertriglyceridemia for the following categories:
Basic and Translational Science
Outcomes Research (and/or EMR-related research)
The goals of the research application should focus on understanding the effects of chylomicron and/or triglyceride elevations on cardiovascular and metabolic disease. Specifically, the grant will support 2 fellows, residents, or junior faculty annually to promote quality research and support the development of future researchers and clinicians.
This grant is awarded by an independent review committee on a competitive basis for a maximum of two academic years with the first year guaranteed and the second-year contingent on approval of a progress submission demonstrating progress towards the pre-stated research objectives and ongoing research.
Deadlines and Important Dates Based on Grant Program Approval
Application Deadline – April 1, 2024 Late submissions or incomplete applications will not be considered.
Award notification – May 2, 2024 Grant recipients and their affiliated institutions receive grant notification.
Acceptance Deadline – July 15, 2024 Grant acceptance must be signed by investigator, mentor, and institution and returned to receive grant funds.
Young Investigator Grant Funds
The Young Investigator Grant will be paid directly to the grantee’s institution
Grant will be funded in the amount of $50,000 per year and may be renewable for a second year at the same level provided sufficient progress has been made towards the research objectives and with approval of a progress submission demonstrating progress and ongoing research
The grant may be transferred to another investigator if needed upon renewal for the second year after approval from Ionis (ex. after completion of 1-year fellowship)
Grant may only be used as described in the granted proposal submission
Institution is not limited in the amount of additional support it may provide the investigator
Submissions duplicative of other research, prior submissions of Investigator sponsored studies, or projects focused on competitor products are not eligible for the Young Investigator Grant Program
Applicant Eligibility and Qualifications
Mentors may submit the application on behalf of the investigator if not yet selected; this will allow the institution to know if funding has been secured to support a fellowship position in advance
Investigator must hold a doctorate degree during the grant period
Investigator may not have more than 3 years of post-doctoral research experience
Investigators working full-time and currently in training are eligible to apply, including residents
Applicants with existing tenure-track research positions or senior faculty appointments are ineligible
Investigator must be either a United States citizen, in possession of a current student visa or a permanent alien resident, specifically:
Green Card - permanent residency visa – unlimited duration, can lead to US Citizenship
H1B Visa - the primary US Work Visa for professionals & students from all over the world or in the USA, who work in specialty occupations. Valid up to 6 years, dual intent visa (can apply for Green Card)
E3 Visa - similar to the H1B but is available to Australian Citizens only
TN1 Visa - similar to the H1B but is available to Canadian & Mexican Citizens only
J1 Visa (must be valid until January 2027)
Young Investigator Program Requirements
Funded research must be conducted in an academic or non-profit institution
Grant should broaden the postdoctoral research experience of the young investigator and not be used for further support of preexisting and extensive postdoctoral research training
Funded research must be conducted under the supervision of an experienced mentor at the sponsoring institution
Proposed research must have anticipated completion timeline of 2 years or less
The grant cannot be transferred to an alternate investigator or institution in the event the original institution and investigator dissolve their association without approval by Ionis
Ionis Medical Affairs must be notified, in writing with appropriate justification, immediately if the sponsoring institution anticipates any delay of the term
Expected Outcomes: submission of data for external presentation and/or publication within 2 years of initial funding
Ionis recognizes the importance of Independent Medical Education (IME) and is committed to supporting programs that enhance patient care. Ionis supports targeted high-quality accredited and non-accredited medical education programs to advance excellence in healthcare by improving disease awareness, clinical knowledge, and multidisciplinary management within our therapeutic areas of focus.
IME is defined as education that is evidence-based, fair-balanced, unbiased, and independent of industry influence. Therefore, all aspects related to IME including but not limited to the agenda, content, and faculty, must remain fully independent and be under the sole control of the activity organizers. Ionis will not provide any guidance to the IME provider. All accredited programs must follow the standards set forth in the Accreditation Council for Continuing Medical Education (ACCME) Standards for Integrity and Independence in Accredited Continuing Education.
Requests with multiple potential supporters are preferred. Due to the number of requests received not all submitted requests will be approved or approved at the amount requested. Ionis will consider funding requests in the following therapeutic areas of focus for medical educational programs in the United States:
Therapeutic Areas of Focus
Current treatment challenges, unmet needs of patients, and investigational drugs in late-stage development for this rare disease.
Severe Hypertriglyceridemia including genetic conditions such as Familial Chylomicronemia Syndrome:
Pathophysiology, disease burden, and management of elevated triglycerides.
Current treatment challenges, unmet needs of patient, and investigational drugs in late-stage development.
Grant Submission Process:
All IME grant request applications must be submitted through our online Ionis Medical Grants portal by clicking here:Apply Now. Please note that the Grant requests must be submitted at least 60 calendar days prior to the program/event start date.
The following elements will be required when submitting the online grant request application. The submitter will be able to save their work and continue at another time. In addition to the required fields on our application form, the submitter will have the opportunity to upload PDF documents of additional information which may be relevant or taken into consideration.
Needs Assessment References
Program Learning Objectives
Information if program has been held previously
Designation if program is affiliated with a congress
Partner Organization Information
Funding decision needed by date
Program Start Date
Program End Date
Total Number of Activities Planned
Activity Type (Live in Person, Live Virtual, Hybrid, Enduring)
Number of Speakers/Faculty Members
Activity Target Audience
Expected Number of Attendees
Expected Audience Information
Audience Generation Tactics
Activity Start/End Dates
Accrediting Bodies and Number of Credit Hours
Amount Requested from Ionis
Please note that the recipient of the grant must be an appropriate organization such as a hospital, university, school of medicine, nursing, or pharmacy, a professional society or association, a medical education communication company, or other institution specializing in specific healthcare-related disciplines (e.g., public health, quality improvement). Ionis does not support IME grant requests from healthcare providers, including individual physicians, private practice groups, group purchasing organizations, managed care organizations, preferred provider organizations, or similar institutions.
If you have any questions regarding the Ionis IME Grant program, please email [email protected].
For Technical Support with the Ionis Grant Portal, please contact SteepRock Client Services via email at [email protected] or phone at +1 (718) 576-1406 (M-F 8am – 6pm US ET).
Global and United States IME grants requests for amyloid transthyretin cardiomyopathy (ATTR-CM) and amyloid transthyretin polyneuropathy (ATTR-PM) will now be submitted to and reviewed by our global development and commercialization partner AstraZeneca. Please visit www.astrazenecagrants.com to review the application procedure and/or to submit.
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