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Ionis Pharmaceuticals, Inc.

2855 Gazelle Court Carlsbad, CA 92010

Telephone: 760-931-9200

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Adverse Event Reporting:

To report an Adverse Event or safety concern with use of an Ionis product, please call (800) 491-2664. If you are experiencing a medical emergency, please dial emergency services such as 911 or 112. For any other assistance, please call our Corporate Headquarters: (760) 931-9200

Ionis Investor Contact:

D. Wade Walke, Ph.D.

Vice President, Investor Relations

760-603-2331 Email

Ionis Media Contact:

Roslyn Patterson

Vice President, Corporate Communications

760-603-4679 Email

Ionis Patient Advocacy Contact:

Kristina Bowyer

Vice President, Patient Advocacy

Ionis Data Privacy Contact:

Patrick O’Neil, Esq.

EVP, Legal & General Counsel
Chief Compliance Officer

760-603-2732 Email