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Now Approved in the U.S.
Building on Our Impossible Firsts, We Can Change the Course of Human Health
Ionis is unlocking the rapidly expanding potential of RNA- and DNA-targeted medicines to enable better futures for people living with serious diseases.
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Living with FCS

Our Science and Technology

Rooted in a Deep Understanding of Genetics

The genetic basis of human disease continues to inspire our science and technology as we expand to new therapeutic approaches, while our industry-leading chemistry helps us target the right medicine to the right disease – providing a rich source for future breakthroughs and transformative impact.

WHO WE ARE

Ionis unites groundbreaking science and technology with relentless passion to discover and deliver medicines that enable better futures for people living with serious diseases.

Our commitment to changing lives is a calling that pushes us to deliver the next solution for patients and those who care for them.

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OUR PIPELINE

We have set our sights on providing new solutions across the spectrum of diseases, from common intractable neurologic conditions to cardiometabolic disorders and select areas of high patient needs.

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WORKING TO MAKE EVERY LIFE AS FULL AS POSSIBLE

We push beyond the impossible to unleash the potential of patients – and those who care for them – enabling them to make their own impact on the world.

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CORPORATE RESPONSIBILITY

We believe operating responsibly and sustainably creates long-term value and a positive impact for our company, stakeholders, patients, communities and the broader world.

JOIN OUR TEAM

Seizing the Moment to Unlock the Potential of RNA- and DNA-Targeted Medicines

If you’re driven to deliver on the promise of groundbreaking medicines that empower patients and caregivers to make their own impact on the world, come join us.

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LATEST NEWS FEED

 

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2025-11-13T00:39:00
EST

- Refinancing transaction with proceeds to be utilized to repurchase or repay the 2026 Convertible Notes prior to or at maturity CARLSBAD, Calif. --(BUSINESS WIRE)--Nov. 13, 2025-- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today the pricing of $700.0 million aggregate principal amount of

2025-11-12T16:00:00
EST

CARLSBAD, Calif. --(BUSINESS WIRE)--Nov. 12, 2025-- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Stifel 2025 Healthcare Conference on Thursday, November 13, 2025 Jefferies Global Healthcare

2025-11-11T16:05:00
EST

- Refinancing transaction with proceeds to be utilized to repurchase or repay the 2026 Convertible Notes prior to or at maturity CARLSBAD, Calif. --(BUSINESS WIRE)--Nov. 11, 2025-- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today that it intends to offer, subject to market conditions and

Click here to read an important notice about a cybersecurity incident relating to services provided to WEX Health (an Ionis employee benefits plan administrator).